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EMMX Biotechnology LLC
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Product Name:MRT 10 CAS:330829-30-6 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Basic information |
Product Name: | N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide | Synonyms: | MRT-10;N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide;N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-;MRT-10 >=98% (HPLC);N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide;ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor | CAS: | 330829-30-6 | MF: | C24H23N3O5S | MW: | 465.52 | EINECS: | | Product Categories: | | Mol File: | 330829-30-6.mol | ![N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Structure](CAS/20180703/GIF/330829-30-6.gif) |
| N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Chemical Properties |
storage temp. | 2-8°C | solubility | DMSO: ≥15mg/mL | form | powder | color | white to tan |
Hazard Codes | Xi,N | Risk Statements | 41-50 | Safety Statements | 26-39-61 | RIDADR | UN 3077 9 / PGIII | WGK Germany | 3 |
| N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Usage And Synthesis |
Description | MRT10 is an antagonist of the Smoothened (Smo) receptor with an IC50 value of 0.64 μM in a luciferase reporter assay. It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (IC50 = 0.5 μM) when expressed in HEK293 cells. | Uses | MRT 10, is a novel, high-affinity antagonist smoothened (Smo) receptor antagonist. It displaces labeled cyclopamine from Smo with an IC50 of 500 nM, and inhibits shh-induced Gli-reporter activity in Shh-light2 cells (IC50 = 0.64 μM). |
| N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Preparation Products And Raw materials |
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