N-Desmethyl Regorafenib

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:BAY-751098;BAY751098;Regorafenib metabolite M4;UNII-58I22S7HYD;BAY 751098
CAS:1343498-72-5
Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Amadis Chemical Company Limited
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Products Intro: Product Name:Regorafenib M-4 metabolite
CAS:1343498-72-5
Purity:0.97 Package:mgs,gs,kgs Remarks:A899141
Company Name: QUALITY CONTROL SOLUTIONS LTD.
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Products Intro: Product Name:Regorafenib Impurity 53
CAS:1343498-72-5
Purity:0.95 Package:10mg; 25mg;50mg;100mg Remarks:Brand: QCS; Can provide COA, hydrogen spectrum, mass spectrometry, liquid phase; Level: Pharmaceutical Impurity Standard
Company Name: BOC Sciences  
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Products Intro: Product Name:N-Desmethyl Regorafenib
CAS:1343498-72-5
Purity:98% Remarks:N-Desmethyl Regorafenib is a metabolite of Regorafenib. Regorafenib is useful for the treatment of i
Company Name: ChemStrong Scientific Co.,Ltd  
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Products Intro: Product Name:Regorafenib Impurity 53
CAS:1343498-72-5
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
N-Desmethyl Regorafenib Basic information
Product Name:N-Desmethyl Regorafenib
Synonyms:N-Desmethyl Regorafenib;Regorafenib impurity O;Regorafenib N-Desmethyl Impurity;Regorafenib M-4 metabolite;2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-;Regorafenib metabolite M4;Regorafenib Impurity 53;4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide
CAS:1343498-72-5
MF:C20H13ClF4N4O3
MW:468.79
EINECS:
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Mol File:1343498-72-5.mol
N-Desmethyl Regorafenib Structure
N-Desmethyl Regorafenib Chemical Properties
Melting point >195°C (dec.)
Boiling point 496.8±45.0 °C(Predicted)
density 1.552±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka12.06±0.70(Predicted)
form Solid
color Pale Orange to Pale Red
Safety Information
MSDS Information
N-Desmethyl Regorafenib Usage And Synthesis
UsesN-Desmethyl Regorafenib is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.
N-Desmethyl Regorafenib Preparation Products And Raw materials
Tag:N-Desmethyl Regorafenib(1343498-72-5) Related Product Information
4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Regorafenib Impurity 9 Regorafenib Impurity 10 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]phenoxy]-N-methyl- Regorafenib Impurity 17 4-(4-amino-3-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide INDEX NAME NOT YET ASSIGNED Regorafenib Impurity 16 N-desmethylnizatidine N-DesMethyl N-Ethyl Olanzapine N-DidesMethyl Olopatadine HCl N-DeMethyl Ivabradine Hydrochloride N-DesMethyl TriMebutine-beta-D-Glucuronide N-DidesMethyl TriMebutine HCl 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE N-Desmethyl Regorafenib N-Oxide (M5 Metabolite) Regorafenib Impurity 6 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide