BIS-PEG6-NHS
中文名称 | BIS-PEG6-NHS |
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中文同义词 | 双-六聚乙二醇-琥珀酰亚胺酯;双琥珀酰亚胺酯六聚乙二醇;琥珀酰亚胺酯-六聚乙二醇-琥珀酰亚胺酯;双琥珀酰亚胺酯-PEG6;双(2,5-二氧代吡咯烷-1-基) 4,7,10,13,16,19-六氧杂二十二烷二酸酯;双-PEG6-琥珀酰亚胺酯 |
英文名称 | Bis-PEG6-NHS ester |
英文同义词 | BIS-PEG6-NHS;4,7,10,13,16,19-Hexaoxadocosanedioic acid, 1,22-bis(2,5-dioxo-1-pyrrolidinyl) ester;Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16,19-hexaoxadocosanedioate;Di-NHS Ester-PEG6 |
CAS号 | 1526718-98-8 |
分子式 | C24H36N2O14 |
分子量 | 576.55 |
EINECS号 | |
相关类别 | |
Mol文件 | 1526718-98-8.mol |
结构式 |
BIS-PEG6-NHS 性质
溶解度 | 溶于DMSO、DCM |
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形态 | 粘稠液体 |
颜色 | 无色至浅黄 |
Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.