- m-PEG10-amine
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- $0.00 / 1g
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2024-03-27
- CAS:1383658-09-0
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| m-PEG10-amine Basic information |
Product Name: | m-PEG10-amine | Synonyms: | m-PEG10-amine;3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine;mPEG10-NH2/3,6,9,12,15,18,21,24,27,30-Decaoxahentriacontan-1-amine | CAS: | 1383658-09-0 | MF: | C21H45NO10 | MW: | 471.58 | EINECS: | | Product Categories: | peg | Mol File: | 1383658-09-0.mol | ![m-PEG10-amine Structure](CAS/20200611/GIF/1383658-09-0.gif) |
| m-PEG10-amine Chemical Properties |
Boiling point | 518.9±45.0 °C(Predicted) | density | 1.065±0.06 g/cm3(Predicted) | pka | 8.74±0.10(Predicted) |
| m-PEG10-amine Usage And Synthesis |
Description | m-PEG10-amine is reactive with activated NHS esters to form stable aminde bond. The hydrophilic PEG spacer increases solubility in aqueous media. | Biological Activity | m-PEG10-amine is a non-cleavable ADC linker containing 10 units of PEG, which can be used for the synthesis of antibody drug conjugates (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. | in vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | target | |
| m-PEG10-amine Preparation Products And Raw materials |
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Tag:m-PEG10-amine(1383658-09-0)
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