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(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate

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(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Suppliers list
Company Name: Nanjing Shizhou Biotechnology Co., Ltd
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Products Intro: Product Name:(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate
CAS:1793080-72-4
Purity:98% Package:1g;5g;10g
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:VX-150
CAS:1793080-72-4
Purity:95.06% Package:1mg;68USD|5mg;148USD|10mg;238USD
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
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Products Intro: Product Name:VX-150
CAS:1793080-72-4
Purity:98% HPLC Package:10mg，500mg，1g，5g，21g，more
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:VX-150
CAS:1793080-72-4
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
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Products Intro: Product Name:VX-150
CAS:1793080-72-4
Purity:98% Package:$296.9/5mg;$484.9/10mg;$969.9/25mg;$1464.9/50mg;Bulk package Remarks:98%

(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate manufacturers

  • VX-150
  • VX-150 pictures
  • $115.00 / 1mg
  • 2024-11-19
  • CAS:1793080-72-4
  • Min. Order:
  • Purity: 95.06%
  • Supply Ability: 10g
(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Basic information
Product Name:(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate
Synonyms:(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate;EOS-62073;(4-(2-(4-fluoro-2-methylphenoxy) -4-(trifluoromethyl)benzamido) -2-oxopyridin-1(2H)-yl)methyl dihydrogen phosphate;Benzamide, N-[1,2-dihydro-2-oxo-1-[(phosphonooxy)methyl]-4-pyridinyl]-2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)-;VX-150;Na+ channels,VX-150,indications,Inhibitor,Na channels,orally,inhibit,pain,VX 150,VX150,Sodium Channel;Sorafenib Impurity 86;Pramipexole Impurity 66-d5 Dihydrochloride
CAS:1793080-72-4
MF:C21H17F4N2O7P
MW:516.34
EINECS:
Product Categories:
Mol File:1793080-72-4.mol
(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Structure
(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Chemical Properties
density 1.59±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (242.09 mM; Need ultrasonic)
form Solid
pka1.72±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Usage And Synthesis
UsesVX-150 is an orally active, highly selective NaV1.8 inhibitor. VX-150 has the potential for various pain indications research[1].
IC 50Nav1.8
References[1] Hemme J Hijma, et al. A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults. Pain Med. 2021 Aug 6;22(8):1814-1826. DOI:10.1093/pm/pnab032
(4-(2-(4-fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxo-1l4,2l5-pyridin-1-yl)methyldihydrogenphosphate Preparation Products And Raw materials
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