| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:PKCζ Pseudosubstrate Inhibitor
CAS:799764-07-1
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:PKCθ Pseudosubstrate Inhibitor
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
JiangSu Star Science Co.,Ltd
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| Tel: |
400-605-7200 17312445705 |
| Email: |
sales022@b2star.com |
| Products Intro: |
Product Name:PKCζ Pseudosubstrate Inhibitor (Protein Kinase Cζ Pseudosubstrate Inhibitor)
CAS:799764-07-1
Package:10g; 100g;500g;1kg;5KG;10KG
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| Company Name: |
Shanghai HongTide Biotechnology Co.,Ltd.
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| Tel: |
19961912513 |
| Email: |
sales@hongtide.com |
| Products Intro: |
Product Name:PKCζ/ι pseudosubstrate inhibitor
CAS:799764-07-1
Purity:98%HPLC Package:1mg;10mg;100mg
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| | PKCζ Pseudosubstrate Inhibitor Basic information |
| Product Name: | PKCζ Pseudosubstrate Inhibitor | | Synonyms: | PKCζ Pseudosubstrate Inhibitor;PKC.zeta. Pseudosubstrate Inhibitor;Pseudosubstrate Inhibitor;PKCζ Pseudosubstrate Inhibitor (Protein Kinase Cζ Pseudosubstrate Inhibitor);L-Leucine, L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl- | | CAS: | 799764-07-1 | | MF: | C76H128N30O16 | | MW: | 1718.02 | | EINECS: | | | Product Categories: | | | Mol File: | 799764-07-1.mol |  |
| | PKCζ Pseudosubstrate Inhibitor Chemical Properties |
| density | 1.48±0.1 g/cm3(Predicted) | | solubility | DMF: 20 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid |
| | PKCζ Pseudosubstrate Inhibitor Usage And Synthesis |
| Description | The atypical protein kinase C isoform, PKCζ, is critical for mediating mitogenic signal transduction, cell survival, and some of the physiological actions of insulin.1 PKCζ pseudosubstrate inhibitor is a synthetic peptide that corresponds to a pseudosubstrate domain of this PKC isoform.2 It selectively, reversibly, and substrate-competitively inhibits PKCζ activity and, thus, is used to delineate the signaling functions of PKCζ.3,4,5 | | References | 1. Toker, A. Signaling through protein kinase C Front. Biosci. 3,d1134-d1147(1998).
2. Eichholtz, T., de Bont, D.B.A., de Widt, J., et al. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor J. Biol. Chem. 268(3),1982-1986(1993).
3. Lee, A.W. The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages PLoS One 6(10),e25580(2011).
4. Dang, P.M.C., Fontayne, A., Hakim, J., et al. Protein kinase C ζ phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst J. Immunol. 166,1206-1213(2001).
5. Standaert, M.L., Galloway, L., Karnam, P., et al. Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport J. Biol. Chem. 272(48),30075-30082(1997). |
| | PKCζ Pseudosubstrate Inhibitor Preparation Products And Raw materials |
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