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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:Salicylcurcumin
CAS:1236545-54-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:Salicylcurcumin
CAS:1236545-54-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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order@med-bio.cn |
| Products Intro: |
Product Name:Salicylcurcumin
CAS:1236545-54-2
Purity:98% Package:1mg; 10mg; 5mg Remarks:Medbio
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| Company Name: |
Nanjing Tengyi Biotechnology Co., Ltd
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025-58851786 17714337195 |
| Email: |
sales@tybiochem.com |
| Products Intro: |
Product Name:Salicylcurcumin
CAS:1236545-54-2
Purity:95+% Package:1g;5g
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| | Salicylcurcumin Basic information |
| Product Name: | Salicylcurcumin | | Synonyms: | Salicylcurcumin;(1E,4Z,6E)-5-hydroxy-1,7-bis(2-hydroxyphenyl)hepta-1,4,6-trien-3-one;1,4,6-Heptatrien-3-one, 5-hydroxy-1,7-bis(2-hydroxyphenyl)-, (1E,4Z,6E)- | | CAS: | 1236545-54-2 | | MF: | C19H16O4 | | MW: | 308.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1236545-54-2.mol |  |
| | Salicylcurcumin Chemical Properties |
| Boiling point | 556.1±50.0 °C(Predicted) | | density | 1.319±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml | | form | A crystalline solid | | pka | 8.34±0.60(Predicted) |
| | Salicylcurcumin Usage And Synthesis |
| Description | Curcuminoids are natural and synthetic analogs of curcumin , a natural polyphenol with modulating effects in inflammation, cancer, and immunity.1 Salicylcurcumin is a synthetic curcuminoid which, like bisdemethoxycurcumin , lacks methoxy groups on both phenols. Furthermore, the hydroxyl groups on each phenol are positioned ortho, as in salicylates, rather than in the para position typical of curcuminoids. Salicylcurcumin has antioxidant and anticarcinogenic properties.2,3 Also, it increases the activity of quinone reductase in mouse hepatoma cells in a dose-dependent fashion, doubling activity at 0.3 μM salicylcurcumin.4,5 | | References | 1. Grynkiewicz, G., and Slifirski, P. Curcumin and curcuminoids in quest for medicinal status Acta Biochim. Pol. 59(2),201-212(2012).
2. Manju, M., Sherin, T.G., Rajasekharan, K.N., et al. Curcumin analogue inhibits lipid peroxidation in a freshwater teleost, Anabas testudineus (Bloch)--an in vitro and in vivo study Fish Physiol. Biochem. 35(3),413-420(2009).
3. Anto, R.J., George, J., Babu, K.V., et al. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids Mutat. Res. 370(2),127-131(1996).
4. Dinkova-Kostova, A.T., and Talalay, P. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes Carcinogenesis 20(5),911-914(1999).
5. Magesh, S., Chen, Y., and Hu, L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents Med. Res. Rev. 32(4),687-726(2012). |
| | Salicylcurcumin Preparation Products And Raw materials |
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