Mambalgin 1

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Mambalgin 1 Basic information
Product Name:Mambalgin 1
Synonyms:Mambalgin 1;Mambalgin 1 USP/EP/BP;Mambalgin 1 TFA
CAS:1609937-15-6
MF:C272H429N85O84S9
MW:6522.42076
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Mol File:1609937-15-6.mol
Mambalgin 1 Structure
Mambalgin 1 Chemical Properties
Safety Information
MSDS Information
Mambalgin 1 Usage And Synthesis
UsesMambalgin-1 is a toxin isolated from black mamba venom. Mambalgin-1 is a disulfide-rich polypeptide consisting of 57 amino acids and belongs to the family of three-finger toxins. Mambalgin-1 can bind to and stabilize ASICs (acid-sensing ion channels) in a physiologically relevant closed-channel conformation[1].
References[1] Sun D, et al. Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect. Cell Discov. 2018;4:27. Published 2018 Jun 5. DOI:10.1038/s41421-018-0026-1
Mambalgin 1 Preparation Products And Raw materials
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