Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:Argatroban-d3 hydrochloride CAS:1356847-56-7 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
Cato Research Chemicals Inc.
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Tel: |
020-81215950 4000-868-328 |
Email: |
customer@uwalab.com |
Products Intro: |
Product Name:Argatroban Impurity 23 CAS:1356847-56-7 Purity:95%(HPLC) Package:10mg;25mg;50mg;100mg
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing1@energy-chemical.com |
Products Intro: |
Product Name:Argatroban-d3 CAS:1356847-56-7 Purity:NULL Package:10mg;1mg Remarks:NULL
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| Argatroban Impurity 23 Basic information |
| Argatroban Impurity 23 Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF: soluble,DMSO: soluble,Methanol: soluble | form | A solid |
| Argatroban Impurity 23 Usage And Synthesis |
Description | Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia. | Uses | Labelled synthetic thrombin inhibitor. Antithrombotic. |
| Argatroban Impurity 23 Preparation Products And Raw materials |
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