- Mc-?Val-?Ala-?PAB
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- $29.00 / 25mg
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2025-04-27
- CAS:1870916-87-2
- Min. Order:
- Purity: 99.24%
- Supply Ability: 10g
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| | Mc-Val-Ala-PAB Basic information |
| Product Name: | Mc-Val-Ala-PAB | | Synonyms: | Mc-Val-Ala-PAB;L-Alaninamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide;Mc-Val-Ala-PAB-OH;Mc ?Val ?Ala ?PAB,Inhibitor,ADC Linkers,Mc?Val?Ala?PAB,Antibody-drug conjugates linkers,inhibit;6-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]amino]-3-methyl-1-oxo-2-butyl]hexanamide;6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]hexanamide;N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-L-alaninamide | | CAS: | 1870916-87-2 | | MF: | C25H34N4O6 | | MW: | 486.56 | | EINECS: | | | Product Categories: | Linker;ADC LINKER | | Mol File: | 1870916-87-2.mol |  |
| | Mc-Val-Ala-PAB Chemical Properties |
| Boiling point | 828.6±65.0 °C(Predicted) | | density | 1.249±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | Solid | | pka | 13.48±0.70(Predicted) | | color | Off-white to yellow |
| | Mc-Val-Ala-PAB Usage And Synthesis |
| Uses | Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | | IC 50 | Protease Cleavable Linker; Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | Mc-Val-Ala-PAB Preparation Products And Raw materials |
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