PROPARGYL-PEG7-NHS ESTER
中文名称 | PROPARGYL-PEG7-NHS ESTER |
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中文同义词 | 丙炔-七聚乙二醇-琥珀酰亚胺酯;丙炔-七聚乙二醇-NHS酯;2,5-二氧代吡咯烷-1-基 4,7,10,13,16,19,22-七氧杂二十五烷-24-炔-1-酸酯;丙炔-七聚乙二醇-活性脂 |
英文名称 | Propargyl-PEG7-NHS ester |
英文同义词 | Propargyl-PEG7-NHS ester;Propargyl-PEG6-CH2CH2COONHS;4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;2,5-Dioxopyrrolidin-1-yl 4,7,10,13,16,19,22-heptaoxapentacos-24-yn-1-oate;Propargyl-PEG6-C2-CONHS ester;Propargyl-PEG6-CH2CH2COONHS/4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester |
CAS号 | 2093152-77-1 |
分子式 | C22H35NO11 |
分子量 | 489.51 |
EINECS号 | |
相关类别 | |
Mol文件 | 2093152-77-1.mol |
结构式 |
PROPARGYL-PEG7-NHS ESTER 性质
沸点 | 562.7±60.0 °C(Predicted) |
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密度 | 1.21±0.1 g/cm3(Predicted) |
Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.