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| LX-2343 Basic information |
Product Name: | LX-2343 | Synonyms: | LX-2343;LX2343;LX-2343;LX 2343;Acetamide, N-1,3-benzodioxol-5-yl-2-[(5-chloro-2-methoxyphenyl)(phenylsulfonyl)amino]-;2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide;Autophagy,PI3K,Amyloid-β,Inhibitor,β-Secretase,Beta-secretase,LX-2343,LX2343,inhibit,BACE,Phosphoinositide 3-kinase,β-amyloid peptide,LX 2343,Abeta | CAS: | 333745-53-2 | MF: | C22H19ClN2O6S | MW: | 474.91 | EINECS: | | Product Categories: | | Mol File: | 333745-53-2.mol | ![LX-2343 Structure](CAS/20180808/GIF/333745-53-2.gif) |
| LX-2343 Chemical Properties |
storage temp. | Store at -20°C | solubility | DMSO:73.33(Max Conc. mg/mL);154.41(Max Conc. mM) DMF:33.0(Max Conc. mg/mL);69.49(Max Conc. mM) | form | A solid | color | White to off-white |
| LX-2343 Usage And Synthesis |
Uses | LX-2343, is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. It has also shown activity as a non-ATP competitive PI3K inhibitor. LX2343 stimulates autophagy in its promotion of Aβ clearance. |
| LX-2343 Preparation Products And Raw materials |
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