|
|
| | LX-2343 Basic information |
| Product Name: | LX-2343 | | Synonyms: | LX-2343;LX2343;LX-2343;LX 2343;Acetamide, N-1,3-benzodioxol-5-yl-2-[(5-chloro-2-methoxyphenyl)(phenylsulfonyl)amino]-;2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide;Autophagy,PI3K,Amyloid-β,Inhibitor,β-Secretase,Beta-secretase,LX-2343,LX2343,inhibit,BACE,Phosphoinositide 3-kinase,β-amyloid peptide,LX 2343,Abeta | | CAS: | 333745-53-2 | | MF: | C22H19ClN2O6S | | MW: | 474.91 | | EINECS: | | | Product Categories: | | | Mol File: | 333745-53-2.mol |  |
| | LX-2343 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:73.33(Max Conc. mg/mL);154.41(Max Conc. mM)
DMF:33.0(Max Conc. mg/mL);69.49(Max Conc. mM) | | form | A solid | | color | White to off-white |
| | LX-2343 Usage And Synthesis |
| Uses | LX-2343, is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. It has also shown activity as a non-ATP competitive PI3K inhibitor. LX2343 stimulates autophagy in its promotion of Aβ clearance. |
| | LX-2343 Preparation Products And Raw materials |
|