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4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:4-CPPC
CAS:29553-70-6
Package:1 mg；10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:4-CPPC
CAS:29553-70-6
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel: +86-18341751992 +86-15382112998
Email: 757984502@qq.com
Products Intro: Product Name:4-CPPC
CAS:29553-70-6
Purity:98 Package:500mg；1g；5g；10g；25g Remarks:Provide customized services
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:4-CPPC
CAS:29553-70-6
Purity:99% Package:$150.9/5mg;$250.9/10mg;$550.9/25mg;$950.9/50mg;Bulk package Remarks:99%
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139
Email: orders@jknbiochem.com
Products Intro: Product Name:4-CPPC
CAS:29553-70-6
Purity:0.98 Package:10G:100G
4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Basic information
Product Name:4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
Synonyms:4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid;4-CPPC (4CPPC);2,5-Pyridinedicarboxylic acid, 4-(3-carboxyphenyl)-;4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid
CAS:29553-70-6
MF:C14H9NO6
MW:287.22
EINECS:
Product Categories:
Mol File:29553-70-6.mol
4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Structure
4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Chemical Properties
storage temp. Store at -20°C
solubility DMSO: soluble
form A crystalline solid
color White to off-white
Safety Information
MSDS Information
4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Usage And Synthesis
Biological Activity4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 μM).1 It is selective for MIF-2 over MIF-1 (IC50 = 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
References1.Tilstam, P.V., Pantouris, G., Corman, M., et al.A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activityJ. Biol. Chem.294(49)18522-18531(2019)
4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Preparation Products And Raw materials
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