| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:affinity isolated antibody Remarks:affinity isolated antibody, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-HUMAN IGM (MU-CHAIN SPECIFIC)-PEROXIDASE Basic information |
| | ANTI-HUMAN IGM (MU-CHAIN SPECIFIC)-PEROXIDASE Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-HUMAN IGM (MU-CHAIN SPECIFIC)-PEROXIDASE Usage And Synthesis |
| Uses | Goat anti-human IgM (mu-chain specific)-peroxidase antibody can be used:
- for dot blot (1:100,000) and immunohistochemistry (1:200 using formalin-fixed, paraffin-embedded sections) applications.
- in immunoblotting
- sandwich immunoassay
| | General Description | B cells predominantly secrete IgM antibodies as pentamers, but may also secrete them as hexamers which are capable of activating the complement cascade more efficiently.
Goat anti-human IgM (mu-chain specific)-peroxidase antibody is specific for human IgM and does not bind to other human Igs. Furthermore, the antibody does not react with mouse and rat IgG. Hence, the antibody conjugate yields reduced background with mouse or rat samples. | | Biochem/physiol Actions | IgM plays a key role in engulfing of the apoptotic cells. A reduction in serum IgM levels leads to increased autoimmune response and higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating clearance of tissue based molecules. |
| | ANTI-HUMAN IGM (MU-CHAIN SPECIFIC)-PEROXIDASE Preparation Products And Raw materials |
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