Company Name: |
Riedel-de Haen AG
|
Tel: |
800 558-9160 |
Email: |
|
Products Intro: |
Remarks:clone SBK10, purified immunoglobulin, buffered aqueous solution
|
Company Name: |
SIGMA-RBI
|
Tel: |
800 736 3690 (Orders) |
Email: |
|
Products Intro: |
|
|
| ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) Basic information |
Product Name: | ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) | Synonyms: | ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU);Anti-PTPμ;Monoclonal Anti-Protein Tyrosine Phosphatase μ antibody produced in mouse;Pcp2;Pcp-2;Protein PCD-5;Purkinje cell protein 2;Purkinje cell-specific protein L7 | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | ![ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) Structure]() |
| ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
| ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) Usage And Synthesis |
Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | General Description | Protein tyrosine phosphatase receptor type U (PTPRU) is also termed as purkinje cell protein 2 (PCP2)/ PTPλ. It belongs to the R2B subfamily of receptor protein tyrosine phosphatases (RPTPs). This gene is located on human chromosome 1p35.3. | Biochem/physiol Actions | Protein tyrosine phosphatase receptor type U (PTPRU) negatively modulates the growth and migration of colon cancer cells. It participates in cell adhesion and acts as tumor suppressors. Knockdown of PTPRU helps to prevent the development of gastric cancer. In gastric cancer cells, PTPRU controls tyrosine phosphorylation and transcriptional activity of β-catenin. It is essential for glioma cell motility and in vivo glioma progression. |
| ANTI-PROTEIN TYROSINE PHOSPHATASE MU (PTP MU) Preparation Products And Raw materials |
|