| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:RK-20448
CAS:479501-40-1
Purity:≥98% Remarks:RK-20448 is the cis-isomer of A-419259. RK-20448 acts as an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 μM, respectively).
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:RK-20448
CAS:479501-40-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:RK20448-Trihydrochloride
CAS:479501-40-1
Purity:NULL Package:100mg;10mg;25mg;50mg Remarks:NULL
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| | RK-20448 Basic information |
| Product Name: | RK-20448 | | Synonyms: | RK-20448;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[cis-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-;RK20449 HCK inhibitor (Cis);RK20449 HCK inhibitor (Trans);7-((1s,4s)-4-(4-methylpiperazin-1-yl)cyclohexyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (relative stereochemistry shown) | | CAS: | 479501-40-1 | | MF: | C29H34N6O | | MW: | 482.62 | | EINECS: | | | Product Categories: | | | Mol File: | 479501-40-1.mol |  |
| | RK-20448 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: 10 mM | | form | A solid |
| | RK-20448 Usage And Synthesis |
| Uses | RK 20448-Trihydrochloride is a relative of A 419259 Trihydrochloride (A101040), which is the hydrochloride form of A 419259, a Src kinase inhibitor and can be used in treatment of chronic myelogenous leukemia, lymphangioleiomyomatosis and tuberous sclerosis. |
| | RK-20448 Preparation Products And Raw materials |
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