Company Name: |
BOC Sciences
|
Tel: |
16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:GK187 CAS:1071001-50-7 Purity:95% Package:1G;10G;100G Remarks:GK187 is a highly potent and selective inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2).
|
Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:GK187 CAS:1071001-50-7 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
|
Product Name: | GK187 | Synonyms: | GK187;GK-187,GK187;3-Heptanone, 1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)-;1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)-3-heptanone | CAS: | 1071001-50-7 | MF: | C14H15F5O2 | MW: | 310.26 | EINECS: | | Product Categories: | | Mol File: | 1071001-50-7.mol | |
| GK187 Chemical Properties |
Boiling point | 330.3±42.0 °C(Predicted) | density | 1.225±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF:10.0(Max Conc. mg/mL);32.23(Max Conc. mM) DMSO:30.0(Max Conc. mg/mL);96.69(Max Conc. mM) Ethanol:10.0(Max Conc. mg/mL);32.23(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.97(Max Conc. mM) | form | Liquid | color | Colorless to light yellow |
| GK187 Usage And Synthesis |
Description | GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism. It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition, respectively. | Uses | GK187 is a very potent and selective GVIA iPLA2 inhibitor. |
| GK187 Preparation Products And Raw materials |
|