| Company Name: |
Struchem Co., Ltd.
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| Tel: |
0512-0512-63009836 15365350169 |
| Email: |
helen@struchem.com |
| Products Intro: |
Product Name:GS143
CAS:916232-21-8
Purity:95 Package:100mg;250mg;500mg
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| Product Name: | GS 143 | | Synonyms: | GS 143;4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid;4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation;Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]- | | CAS: | 916232-21-8 | | MF: | C28H19FN2O4 | | MW: | 466.46 | | EINECS: | | | Product Categories: | | | Mol File: | 916232-21-8.mol |  |
| | GS 143 Chemical Properties |
| Boiling point | 667.9±65.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF:25.0(Max Conc. mg/mL);53.59(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.43(Max Conc. mM)
DMSO:31.38(Max Conc. mg/mL);67.28(Max Conc. mM) | | form | A crystalline solid | | pka | 4.20±0.10(Predicted) | | color | Pink to red |
| | GS 143 Usage And Synthesis |
| Uses | 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic Acid blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells. | | storage | Store at +4°C |
| | GS 143 Preparation Products And Raw materials |
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