MLN-4760 manufacturers
- MLN-4760
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- $187.00 / 1mg
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2024-11-19
- CAS:305335-31-3
- Min. Order:
- Purity: 99.05%
- Supply Ability: 10g
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| | MLN-4760 Basic information |
| Product Name: | MLN-4760 | | Synonyms: | MLN-4760;L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-;((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine;inhibit,Angiotensin-converting Enzyme (ACE),MLN 4760,Inhibitor,MLN-4760,MLN4760;(2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)methyl]-1H-imidazol-5-yl}ethyl]amino}-4-methylpentanoic acid | | CAS: | 305335-31-3 | | MF: | C19H23Cl2N3O4 | | MW: | 428.31 | | EINECS: | | | Product Categories: | | | Mol File: | 305335-31-3.mol |  |
| | MLN-4760 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: soluble | | form | A solid | | color | Off-white to light yellow |
| | MLN-4760 Usage And Synthesis |
| Definition | ChEBI: MLN-4760 is a L-histidine derivative that is L-histidine in which a hydrogen of the primary amino group is substituted by a (1S)-1-carboxy-3-methylbutyl group and the ring NH group is substituted by a 3,5-dichlorobenzyl group. It is a potent and selective human angiotensin-converting enzyme 2 (ACE2) inhibitor (IC50 = 0.44 nM) which was in clinical development for the treatment of ulcerative colitis. It has a role as an anti-inflammatory agent and an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. It is a L-histidine derivative, a dichlorobenzene and a L-leucine derivative. | | storage | Store at -20°C |
| | MLN-4760 Preparation Products And Raw materials |
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