| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:GGTI-2133
CAS:191102-79-1
Package:1Mg,25Mg,5Mg
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:GGTI-2133
CAS:191102-79-1
Purity:NULL Package:1mg;25mg;5mg Remarks:NULL
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| | GGTI 2133 Basic information |
| | GGTI 2133 Chemical Properties |
| Melting point | 103-118.5 °C | | storage temp. | −20°C | | solubility | DMSO: 25 mg/mL | | form | solid | | color | white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | GGTI 2133 Usage And Synthesis |
| Uses | GGTI-2133 i an inhibitors of protein geranylgeranyltransferase-I. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast. GGTI-2133 inhibited proliferation and migration via involvement of RhoA and RalB proteins in human oral squamous cell carcinoma cell. | | Definition | ChEBI: GGTI-2133 free base is an N-acyl-L-amino acid obtained by condensation of the carboxy group of 4-{[(imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoic acid with the amino group of L-leucine. An inhibitor of geranylgeranyltransferase type I. It has a role as an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor. It is a L-leucine derivative, a N-acyl-L-amino acid, a member of naphthalenes, a biaryl, a member of imidazoles, a member of benzamides, a substituted aniline and a secondary amino compound. It is a conjugate base of a GGTI-2133 free base(1+). |
| | GGTI 2133 Preparation Products And Raw materials |
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