Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Mitochondria Staining Kit Purity:1 kit sufficient for 40 tests (of 5 mL cell suspensions), 1 Package:1KT Remarks:CS0390-1KT
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| MITOCHONDRIA STAINING KIT Basic information |
| MITOCHONDRIA STAINING KIT Chemical Properties |
Hazard Codes | Xn | Risk Statements | 21/22 | Safety Statements | 36-36/37 | WGK Germany | 3 |
| MITOCHONDRIA STAINING KIT Usage And Synthesis |
Uses | The dissipation of the mitochondrial electrochemical potential gradient (Δψ) is known as an early event in apoptosis. This kit offers a fast and convenient method for the detection of changes in mitochondrial inner-membrane electrochemical potential in living cells using the cationic, lipophilic dye, JC-1. | General Description | In normal cells, the JC-1 dye concentrates in the mitochondrial matrix where it forms red fluorescent aggregates. Any event that dissipates the mitochondrial membrane potential (e.g. apoptosis) prevents the accumulation of the JC-1 dye in the mitochondria and thus, the dye is dispersed throughout the entire cell leading to a shift from red (JC-1-aggregates) to green fluorescence (JC-1 monomers). The fluorescence of the cells stained with this kit may be observed by fluorescence microscopy or measured by fluorimetric and flow cytometry analysis. |
| MITOCHONDRIA STAINING KIT Preparation Products And Raw materials |
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