| Company Name: |
Shanghai Balmxy Pharmaceutical Co., Ltd
|
| Tel: |
021-24206007 13764915196 |
| Email: |
sales@balmxy.com |
| Products Intro: |
Product Name:Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-
CAS:104676-09-7
Purity:98%+ Package:5g;25g;100g;500g;1kg;5kg;25kg;100kg
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| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
|
| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:MCC
CAS:104676-09-7
Purity:95% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- manufacturers
- MCC
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- $0.00 / 50mg
-
2024-03-27
- CAS:104676-09-7
- Min. Order: 50mg
- Purity: >95.00%
- Supply Ability: 50mg
|
| | Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- Basic information |
| | Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- Chemical Properties |
| Boiling point | 468.5±14.0 °C(Predicted) | | density | 1.280±0.06 g/cm3(Predicted) | | form | Solid | | pka | 16.71±0.40(Predicted) | | color | Light yellow to brown |
| | Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- Usage And Synthesis |
| Biological Activity | MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].
Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1]. | | References | [1]. Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24(9):1566-1573. |
| | Cyclohexanecarboxamide, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- Preparation Products And Raw materials |
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