Company Name: |
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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Tel: |
400-400-6206333 18521732826 |
Email: |
market@aladdin-e.com |
Products Intro: |
Product Name:Rhodamine Phenylglyoxal Monohydrate CAS:2309313-01-5 Package:0.5mg/RMB 5199.90
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Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:Citrulline-specific Probe-Rhodamine Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:Citrulline-specific Probe-rhodamine CAS:2309313-01-5 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
Shanghai Universal Biotech Co.,Ltd
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Tel: |
18768175414 |
Email: |
gaojun@univ-bio.com |
Products Intro: |
Product Name:Citrulline-specific Probe-rhodamine Package:1mg Remarks: 见优宁维官网
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| Citrulline-specific Probe-rhodamine Basic information |
| Citrulline-specific Probe-rhodamine Chemical Properties |
storage temp. | Store at -20°C | solubility | Acetonitrile:Water (2:1): 1 mg/ml; DMF: 1 mg/ml | form | A lyophilized solid |
| Citrulline-specific Probe-rhodamine Usage And Synthesis |
Description | Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has been observed in a host of human diseases. Citrulline-specific probe-rhodamine is a highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline. This chemical probe (comprised of a single isomer) is capable of reacting with any citrulline-containing protein and can be analyzed with fluorescent imaging (excitation 532 nm; emission 580 nm). When added at 100 μM for 30 minutes at acidic pH, this probe has a reported limit of detection of ~10 ng for citrullinated histone H3 and ~1 ng for autodeiminated PAD4. | Uses | Rhodamine Phenylglyoxal Hydrate is a citrulline-specific chemical probe which can be used to detect protein citrullination through a chemoselective reaction between glyoxal and citrulline. |
| Citrulline-specific Probe-rhodamine Preparation Products And Raw materials |
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