| Company Name: |
Shanghai Yunpun industrial Co.,Ltd
|
| Tel: |
21-61726900 15202122459 |
| Email: |
sales@yunpun.com |
| Products Intro: |
Product Name:PF-06456384 trihydrochloride
CAS:1834610-75-1
Purity:95% Package:1ASSAYS
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| Company Name: |
Beijing Biocreative Technology Co., Ltd.
|
| Tel: |
15522676233 |
| Email: |
3007606172@qq.com |
| Products Intro: |
Product Name:PF-06456384 trihydrochloride
CAS:1834610-75-1
Purity:99% HPLC Package:5.0mg; 25.0mg
|
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| | PF-06456384 trihydrochloride Basic information |
| | PF-06456384 trihydrochloride Chemical Properties |
| storage temp. | Store at -20°C | | form | Solid | | color | White to off-white |
| | PF-06456384 trihydrochloride Usage And Synthesis |
| Biological Activity | PF-06447475 trihydrochloride is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 trihydrochloride can be used for parkinson's disease (PD) research[1]. | | References | [1]. Jaclyn L Henderson, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32. |
| | PF-06456384 trihydrochloride Preparation Products And Raw materials |
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