Company Name: |
Jilin Province Woda Biotechnology Co., Ltd.
|
Tel: |
13504435624 |
Email: |
1927928688@qq.com |
Products Intro: |
Product Name:3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine CAS:2378619-75-9 Purity:98%
|
Company Name: |
Elucigen bio
|
Tel: |
13501719342 |
Email: |
wayne.zheng@elucigenbio.com |
Products Intro: |
Product Name:3-[({[1,1'-biphenyl]-4-yl}methyl)sulfanyl]-6-methyl-1,2,4,5-tetrazine CAS:2378619-75-9 Purity:97% LC/GC Package:10mg;25mg;50mg;100mg;250mg;500mg;1g;5g;10g Remarks:For research use only
|
|
| 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Basic information |
Product Name: | 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- | Synonyms: | 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl-;3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine;3-[({[1,1'-biphenyl]-4-yl}methyl)sulfanyl]-6-methyl-1,2,4,5-tetrazine | CAS: | 2378619-75-9 | MF: | C16H14N4S | MW: | 294.37 | EINECS: | | Product Categories: | | Mol File: | 2378619-75-9.mol | |
| 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Chemical Properties |
Boiling point | 520.7±53.0 °C(Predicted) | density | 1.29±0.1 g/cm3(Predicted) | pka | 0.46±0.11(Predicted) |
| 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Usage And Synthesis |
Uses | 3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine (b-Tz) is a minimal tetrazine derivative capable of undergoing [4+2] Diels-Alder cycloaddition reactions with strained alkenes, which makes it highly useful in bioorthogonal labeling and cell detection applications. Tetrazines are often incorporated into chemical probes or other small-molecule tools using linkers that may impact physicochemical properties or the performance of the resulting conjugate product. Here, Lambert et al demonstrated the linker-free incorporation of b-Tz via silver-mediated Liebeskind-Srogl cross-coupling with a variety of aryl and heteroaryl boronic acids. This ″minimal″ tetrazine approach will facilitate the introduction of tetrazine into diverse complex molecules and improved probes for live-cell imaging and in vivo chemistry.
Supporting products PdCl2(dppf): 697230 Ag2O: 226831 |
| 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Preparation Products And Raw materials |
|