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4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide

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4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide Basic information
Product Name:4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide
Synonyms:4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide
CAS:1257864-28-0
MF:C13H12FN3O2
MW:261.26
EINECS:
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Mol File:1257864-28-0.mol
4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide Structure
4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide Chemical Properties
Safety Information
MSDS Information
4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide Usage And Synthesis
Uses4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide is an intermediate for the synthesis of Regorafenib-d3 (R143002), which is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.
4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide Preparation Products And Raw materials
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