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1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-

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1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Suppliers list
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Tel: 13504435624
Email: 1927928688@qq.com
Products Intro: Product Name:5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,
CAS:2357113-68-7
Purity:98% Package:1克;5克;100克
Company Name: Changzhou Bojia Biomedical Technology Co., Ltd.  
Tel: 2122619822
Email: czbjpharma@126.com
Products Intro: Product Name:5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1 ,3(2H)-dione,
CAS:2357113-68-7
Purity:99% Package:1g/10g/100g/1kg
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.  
Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Products Intro: Product Name:5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,
CAS:2357113-68-7
Purity:>=98% Package:1kg；25kg
1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Basic information
Product Name:1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-
Synonyms:1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-;5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione,;5-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethyl)piperazin-1-yl]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
CAS:2357113-68-7
MF:C25H35N5O7
MW:517.57
EINECS:
Product Categories:
Mol File:2357113-68-7.mol
1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Structure
1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Chemical Properties
Boiling point 727.2±60.0 °C(Predicted)
density 1.312±0.06 g/cm3(Predicted)
pka10.83±0.40(Predicted)
Safety Information
MSDS Information
1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Usage And Synthesis
Biological ActivityThalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References[1]. Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1001.
1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)- Preparation Products And Raw materials
Tag:1H-Isoindole-1,3(2H)-dione, 5-[4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-1-piperazinyl]-2-(2,6-dioxo-3-piperidinyl)-(2357113-68-7) Related Product Information