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| INDEX NAME NOT YET ASSIGNED Basic information |
| INDEX NAME NOT YET ASSIGNED Chemical Properties |
form | Solid | color | Light yellow to yellow |
| INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
Biological Activity | Me VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032 for use as a precursor to a PROTAC? that hijacks VHL as the E3 ubiquitin ligase component. Me VH 032, amine is supplied with a primary amine functional handle, for ready conjugation to a linker/target protein ligand. Introduction of the methyl group at the benzylic position of VH 032 is associated with improved binding affinity. | storage | Desiccate at RT |
| INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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