Azaphen hydrochloride manufacturers
- Azaphen
-
- $81.00 / 100mg
-
2024-11-19
- CAS:24853-80-3
- Min. Order:
- Purity: 97.62%
- Supply Ability: 10g
|
| | Azaphen hydrochloride Basic information |
| Product Name: | Azaphen hydrochloride | | Synonyms: | AZAPHENONXAZINE;azaphen;2-(4-Methyl-1-piperazinyl)-10-methyl-3,4-diazphenoxazine dihydrochloride;Azafen;Pipofezin hydrochloride;Pipofezine hydrochloride;Azaphen (Pipofezine);Azaphen hydrochloride | | CAS: | 24853-80-3 | | MF: | C16H19N5O.2ClH | | MW: | 370.28 | | EINECS: | | | Product Categories: | | | Mol File: | 24853-80-3.mol |  |
| | Azaphen hydrochloride Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Solid |
| Toxicity | LD50 orl-rat: 1 g/kg ZPPLBF 114,787,75 |
| | Azaphen hydrochloride Usage And Synthesis |
| Uses | Pipofezine(Azafen or Azaphen) is a potent inhibitor of the reuptake of serotonin.
IC50 Value:
Target: SSRIs
Pipofezine is a tricyclic antidepressant (TCA) approved in Russia for the treatment of depression. | | Safety Profile | Poison by ingestion, intravenous,and subcutaneous routes. When heated to decompositionit emits very toxic fumes of HCl and NOx. Anantidepressant. | | References | [1] Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(5), 237-241.
[2] Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6. PMID:16281382
[3] Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33. PMID:557800
[4] Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32. PMID:1112390
[5] Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6. PMID:4450998 |
| | Azaphen hydrochloride Preparation Products And Raw materials |
|