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| | 2-Butanone, 1,1'-[cyclohexylidenebis[(2-methyl-4,1-phenylene)oxy]]bis[3,3-dimethyl- Basic information |
| | 2-Butanone, 1,1'-[cyclohexylidenebis[(2-methyl-4,1-phenylene)oxy]]bis[3,3-dimethyl- Chemical Properties |
| Boiling point | 582.5±50.0 °C(Predicted) | | density | 1.041±0.06 g/cm3(Predicted) |
| | 2-Butanone, 1,1'-[cyclohexylidenebis[(2-methyl-4,1-phenylene)oxy]]bis[3,3-dimethyl- Usage And Synthesis |
| Description | LG190119 is a nonsecosteroidal vitamin D receptor modulator inhibits the growth of LNCaP xenograft tumors in athymic mice without increased serum calcium. LG190119 effectively inhibited LNCaP xenograft tumor growth without increased serum calcium levels or any other apparent side effects. Compounds of this class may represent promising new therapeutics for treatment of prostate cancer and other cancers with fewer undesirable side effects than currently used drugs. | | in vivo | In the established tumor study, LG190119 at each dose resulted in significant tumor growth inhibition without hypercalcemia at both 10 and 15 days. LG190119 effectively inhibited LNCaP xenograft tumor growth without increased serum calcium levels or any other apparent side effects._x000D_
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Reference: Prostate. 2001 Nov 1;49(3):224-33. https://pubmed.ncbi.nlm.nih.gov/11746268/ | | target | LG190119 is a nonsecosteroidal vitamin D receptor modulator inhibits the growth of LNCaP xenograft tumors in athymic mice without increased serum calcium. |
| | 2-Butanone, 1,1'-[cyclohexylidenebis[(2-methyl-4,1-phenylene)oxy]]bis[3,3-dimethyl- Preparation Products And Raw materials |
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