| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-CD59
Purity:Prestige Antibodies P Package:100μL Remarks:HPA026494
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| | ANTI-HUMAN CD59 Basic information |
| Product Name: | ANTI-HUMAN CD59 | | Synonyms: | Anti-MIRL;Monoclonal Anti-CD59 antibody produced in mouse;Monoclonal Anti-CD59-Biotin antibody produced in mouse;Monoclonal Anti-CD59 azide free antibody produced in mouse;Anti-CD59 antibody produced in rabbit;Monoclonal Anti-CD59-FITC antibody produced in mouse;Monoclonal Anti-CD59-PE antibody produced in mouse;Monoclonal Anti-CD59-APC antibody produced in mouse | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN CD59 Structure]() |
| | ANTI-HUMAN CD59 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 |
| | ANTI-HUMAN CD59 Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. (provided by RefSeq) |
| | ANTI-HUMAN CD59 Preparation Products And Raw materials |
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