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TMC-205

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TMC-205 Basic information
Product Name:TMC-205
Synonyms:TMC-205;1H-Indole-3-carboxylic acid, 6-[(1E)-3-methyl-1,3-butadien-1-yl]-
CAS:403646-00-4
MF:C14H13NO2
MW:227.26
EINECS:
Product Categories:
Mol File:403646-00-4.mol
TMC-205 Structure
TMC-205 Chemical Properties
Boiling point 478.3±25.0 °C(Predicted)
density 1.239±0.06 g/cm3(Predicted)
pka3.88±0.10(Predicted)
Safety Information
MSDS Information
TMC-205 Usage And Synthesis
DescriptionMC-205 is a new transcriptional up-regulator and a natural fungal metabolite with antiproliferative activity against cancer cell lines. Expression of the luciferase activity was activated ca. 2-, 4-, and 6-fold by 1, 10, and 100 microM TMC-205, respectively. TMC-205 activated the transcriptional activity in a manner dependent on the presence of the enhancer element of SV40 in its promoter region.
TMC-205 Preparation Products And Raw materials
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