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| | desmethylanethol trithione Basic information |
| Product Name: | desmethylanethol trithione | | Synonyms: | desmethylanethol trithione;Adt-Oh;ACS 1;5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione;Anethole impurity 2;5-(4-hydroxyphenyl)dithiole-3-thione;Anethole Trithione impurity 2;3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)- | | CAS: | 18274-81-2 | | MF: | C9H6OS3 | | MW: | 226.34 | | EINECS: | | | Product Categories: | | | Mol File: | 18274-81-2.mol |  |
| | desmethylanethol trithione Chemical Properties |
| Melting point | 191-192 °C | | Boiling point | 431.4±55.0 °C(Predicted) | | density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 1 mg/ml | | form | A crystalline solid | | pka | 9.78±0.30(Predicted) | | color | Yellow to brown |
| | desmethylanethol trithione Usage And Synthesis |
| Description | ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras. | | Uses | is used in method for preventing or treating diseases associated with administration of VEGFR and/or VEGF inhibitor. |
| | desmethylanethol trithione Preparation Products And Raw materials |
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