115607-61-9
中文名称 | 115607-61-9 |
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中文同义词 | 化合物 T16894 |
英文名称 | 3-butyryl-4-(2-methylphenylamino)-8-methoxyquinoline |
英文同义词 | 3-butyryl-4-(2-methylphenylamino)-8-methoxyquinoline;1-[8-METHOXY-4-[(2-METHYLPHENYL)AMINO]-3-QUINOLINYL]-1-BUTANONE(WXG00349);1-Butanone, 1-[8-methoxy-4-[(2-methylphenyl)amino]-3-quinolinyl]-;SKF96067,SKF-96067 |
CAS号 | 115607-61-9 |
分子式 | C21H22N2O2 |
分子量 | 334.41 |
EINECS号 | |
相关类别 | |
Mol文件 | 115607-61-9.mol |
结构式 | ![]() |
115607-61-9 性质
沸点 | 473.2±45.0 °C(Predicted) |
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密度 | 1.162±0.06 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 3.95±0.50(Predicted) |
SKF96067 是一种可逆的 H+/K+-ATPase 抑制剂。
SKF96067 inhibits K + -stimulated ATPase activity competitively with respect to the activating action K + , with a K i value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC 50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.