| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:LT-540-717
CAS:2143089-35-2
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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LT-540-717 manufacturers
- LT-540-717
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- $2500.00 / 100mg
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2024-10-28
- CAS:2143089-35-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | LT-540-717 Basic information |
| | LT-540-717 Chemical Properties |
| | LT-540-717 Usage And Synthesis |
| Uses | LT-540-717 (compound 32) is a potent FLT3 inhibitor (IC50=0.62 nM) with antiproliferative activity. LT-540-717 also inhibits several acquired FLT3 mutations, FLT3 (ITD, D835V), FLT3 (ITD, F691L), FLT3 (D835Y) and FLT3 (D835V). LT-540-717 has potential to be an anti-AML agent[1]. | | References | [1] Zhi Y, et al. Rational design of 4-((6-phenoxypyrimidin-4-yl)amino)-N-(4-(piperazin-1-yl)phenyl)-1H-pyrazole-3-carboxamide (LT-540-717) as orally bioavailable FLT3 inhibitor. Eur J Med Chem. 2023 Aug 5;256:115448. DOI:10.1016/j.ejmech.2023.115448 |
| | LT-540-717 Preparation Products And Raw materials |
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