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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
CAS:289893-25-0
Purity:99% Package:25KG;5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Arimoclomol；BRX-220 free base
CAS:289893-25-0
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dorne Chemical Technology co. LTD
Tel: +86-86-13583358881 +8618560316533
Email: Ethan@dornechem.com
Products Intro: Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
CAS:289893-25-0
Purity:0.99
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:arimoclomol
CAS:289893-25-0
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel: +86-18341751992 +86-15382112998
Email: 757984502@qq.com
Products Intro: Product Name:arimoclomol
CAS:289893-25-0
Purity:0.98 Package:100mg;500mg;1g;5g Remarks:existing product
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Basic information
Product Name:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
Synonyms:(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol;arimoclomol;Amrioclomol;Pefcalcitol;(2R-)Arimoclomol NEW;BRX-220 free base;3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide;aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor
CAS:289893-25-0
MF:C14H20ClN3O3
MW:313.78
EINECS:
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Mol File:289893-25-0.mol
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Structure
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Chemical Properties
Melting point 93 - 95o C
Boiling point 539.2±60.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka14.03±0.20(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Usage And Synthesis
UsesArimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Preparation Products And Raw materials
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