CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309)
| 中文名称 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) |
|---|---|
| 中文同义词 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309),LKKFNARRKLKGAILTTMLA;CAMK拮抗剂;N-(3-甲基戊酰基)亮氨酰苏氨酰苏氨酰-N-甲基蛋氨酰胺;蛋白激酶片段 CALMODULIN DEPENDENT PROTEIN KINASEII(290-3 |
| 英文名称 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) |
| 英文同义词 | CALMODULIN-DEPENDENT PROTEIN KINASE II FRAGMENT 290-309;CAM KINASE II (290-309);H-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-ILE-LEU-THR-THR-MET-LEU-ALA-OH;CALMODULIN-DEPENDENT PROTEIN KINASE IIFR AGMENT 290;LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-ILE-LEU-THR-THR-MET-LEU-ALA;LKKFNARRKLKGAILTTMLA;CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309);CALMODULIN DEPENDENT PROTEIN KINASE II |
| CAS号 | 115044-69-4 |
| 分子式 | C103H185N31O24S |
| 分子量 | 2273.83 |
| EINECS号 | |
| 相关类别 | 多肽;标准品;peptide |
| Mol文件 | 115044-69-4.mol |
| 结构式 |  |
CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) 性质
| 密度 | 1.37±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | −20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 白色冻干固体 |
Calmodulin-Dependent Protein Kinase II (290-309) 是有效的 CaMK 拮抗剂， 抑制抑制Ca2+/钙调蛋白依赖性蛋白激酶II的 IC50 值为52 nM。
IC50: 52 nM (calmodulin-dependent protein kinase II)
Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC 50 of 52 nM for inhibition of Ca 2+ /calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity.
安全信息
| 安全说明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 1 mg | 3300元 |
| 2023/03/20 | HY-P1479 | CALMODULIN-DEPENDENT PROTEIN KINASE II (290-309) Calmodulin-Dependent Protein Kinase II (290-309) | 115044-69-4 | 5mg | 13000元 |