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| 5-HYDROXY ISATIN Basic information |
Product Name: | 5-HYDROXY ISATIN | Synonyms: | 5-HYDROXY ISATIN;5-Hydroxy-1H-indole-2,3-dione;5-hydroxyindoline-2,3-dione;5-Hydroxy isatin 5-Hydroxy indole-2,3-dione;1H-Indole-2,3-dione, 5-hydroxy-;5-hydroxy-2,3-dihydro-1H-indole-2,3-dione;Flumazenil Impurity 17 | CAS: | 116569-09-6 | MF: | C8H5NO3 | MW: | 163.13 | EINECS: | | Product Categories: | | Mol File: | 116569-09-6.mol | ![5-HYDROXY ISATIN Structure](CAS/GIF/116569-09-6.gif) |
| 5-HYDROXY ISATIN Chemical Properties |
storage temp. | -20°C | solubility | DMF: 3 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol | form | A solid |
| 5-HYDROXY ISATIN Usage And Synthesis |
Biological Activity | 5-hydroxy Isatin is an inhibitor of monoamine oxidase A (MAO-A; IC50 = 8.4 μM).1 It is selective for MAO-A over MAO-B (IC50 = >100 μM). 5-hydroxy Isatin (50 μM) also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.2 | References | 1.Medvedev, A.E., Goodwin, B., Chow, A., et al.Inhibitory potency of some isatin analogues on human monoamine oxidase A and BBiochem. Pharmacol.44(3)590-592(1992)
2.Medvedev, A.E., Goodwin, B.L., Sandler, M., et al.Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclaseBiochem. Pharmacol.57(8)913-915(1999) |
| 5-HYDROXY ISATIN Preparation Products And Raw materials |
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