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| | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE Basic information |
| Product Name: | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE | | Synonyms: | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE;5-(Pyridin-2-yl)-2(1H)-pyridone;5-(Pyridin-2-yl)-1,2-dihydropyridin-2-one;5-(Pyridin-2-yl)pyridin-2(1H)-one;5-(2-Pyridyl)pyridin-2(1H)-one;5-pyridin-2-yl-1H-pyridin-2-one;5-(2-PYRIDYL)-2-PYRIDONE;2-Hydroxy-5-(2-pyridyl)pyridine | | CAS: | 381233-78-9 | | MF: | C10H8N2O | | MW: | 172.18 | | EINECS: | 206-141-6 | | Product Categories: | API | | Mol File: | 381233-78-9.mol |  |
| | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE Chemical Properties |
| Melting point | 71-75°C | | Boiling point | 434.3±45.0 °C(Predicted) | | density | 1.221±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 10.85±0.10(Predicted) | | form | Solid | | color | White | | InChI | InChI=1S/C10H8N2O/c13-10-5-4-8(7-12-10)9-3-1-2-6-11-9/h1-7H,(H,12,13) | | InChIKey | NHWKTZWOSIVHOL-UHFFFAOYSA-N | | SMILES | C1(C2C=CC(=O)NC=2)=NC=CC=C1 |
| | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE Usage And Synthesis |
| Uses | 5-(2-Pyridyl)-1,2-dihydropyridin-2-one is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission. |
| | 5-(2-PYRIDYL)-1,2-DIHYDROPYRIDIN-2-ONE Preparation Products And Raw materials |
| Raw materials | Propane, 1,1'-oxybis[2,2-dimethyl--->1,3-dimethyl-2,3-dihydro-2-oxopyrimidinium chloride-->2,3'-Bipyridine, 6'-chloro--->2-Bromo-5-(2-pyridyl)pyridine-->2-Pyridineboronic acid-->2-Methoxy-5-pyridineboronic acid-->2(1H)-Pyridinone, 5-acetyl- (9CI)-->2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE-->2-(TRIBUTYLSTANNYL)PYRIDINE-->6-CHLORONICOTINOYL CHLORIDE-->6'-Methoxy-2,3'-bipyridine-->1-Butanol-->2,5-Dibromopyridine-->2-Bromopyridine | | Preparation Products | PeraMpanel-->5'-broMo-[2,3'-bipyridin]-6'(1'H)-one |
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