| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Glycerophospho-N-Oleoyl Ethanolamine
CAS:201738-24-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Glycerophospho-N-OleoylEthanolamine
CAS:201738-24-1
Purity:NULL Package:1mg;2.5mg Remarks:NULL
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:MONO(2,3-DIHYDROXYPROPYL)MONO[2-[[(9Z)-1-OXO-9-OCTADECENYL]AMINO]ETHYL] ESTER PHOSPHORIC ACID
CAS:201738-24-1
Purity:98% Package:10mg; 1mg; 5mg Remarks:Medbio
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Glycerophospho-N-Oleoyl Ethanolamine
CAS:201738-24-1
Purity:98% Package:1mg;5mg;10mg
|
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| | MONO(2,3-DIHYDROXYPROPYL)MONO[2-[[(9Z)-1-OXO-9-OCTADECENYL]AMINO]ETHYL] ESTER PHOSPHORIC ACID Basic information |
| | MONO(2,3-DIHYDROXYPROPYL)MONO[2-[[(9Z)-1-OXO-9-OCTADECENYL]AMINO]ETHYL] ESTER PHOSPHORIC ACID Chemical Properties |
| density | 1.096±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≤20mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide | | form | crystalline solid | | pka | 1.37±0.50(Predicted) |
| | MONO(2,3-DIHYDROXYPROPYL)MONO[2-[[(9Z)-1-OXO-9-OCTADECENYL]AMINO]ETHYL] ESTER PHOSPHORIC ACID Usage And Synthesis |
| Uses | Glycerophospho-N-Oleoyl Ethanolamine is a precursor to the cannabinoid compound OEA. | | Definition | ChEBI: Glycerophospho-N-Oleoyl Ethanolamine is a glycerophosphoethanolamine. | | Biological Activity | glycerophospho-n-oleoyl ethanolamine is the precursor of oleoyl ethanolamide (oea). the fatty-acid ethanolamide, oleoylethanolamide (oea) is a naturally occurring lipid. oleoylethanolamide is an endogenous ppar-α agonist. oleoylethanolamide has been involved in modulating feeding and energy homeostasis by binding to peroxisome proliferator-activated receptor-alpha (ppar-α) [1]. ppar-α is a transcription factor and a major regulator of lipid metabolism in the liver. activation of ppar-α is mainly involved in fatty acid oxidation and expressed in liver, kidney, and skeletal muscle. through ligand binding, ppar-α promotes uptake, utilization, and catabolism of fatty acids [2].oea reduced food intake and lowered body-weight gain. subchronic oea treatment (5 mg/kg, i.p., once daily for two weeks) in zucker rats initiated transcription of ppar-α and other ppar-α target gene [1]. oea is an endogenous, potent agonist for pparα. oea activated pparα with an ec50 value of 120 nm in a transactivation assay [3]. in rodents, intraperitoneal administration of oea induced satiety and peripheral utilization of lipid substrate. acute oral administration induced satiety [4]. | | references | [1] fu j, oveisi f, gaetani s, et al. oleoylethanolamide, an endogenous ppar-α agonist, lowers body weight and hyperlipidemia in obese rats[j]. neuropharmacology, 2005, 48(8): 1147-1153.
[2] schiffrin e l, amiri f, benkirane k, et al. peroxisome proliferator-activated receptors[j]. hypertension, 2003, 42(4): 664-668.
[3] fu j, gaetani s, oveisi f, et al. oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor ppar-α[j]. nature, 2003, 425(6953): 90-93.
[4] thabuis c, destaillats f, tissot‐favre d, et al. oleoyl‐ethanolamide (oea): a bioactive lipid derived from oleic acid and phosphatidylethanol‐amine[j]. lipid technology, 2007, 19(10): 225-227. |
| | MONO(2,3-DIHYDROXYPROPYL)MONO[2-[[(9Z)-1-OXO-9-OCTADECENYL]AMINO]ETHYL] ESTER PHOSPHORIC ACID Preparation Products And Raw materials |
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