| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:DesMosterol-d6
CAS:1246298-67-8
Package:10Mg,1Mg
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| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:cholesta-5,24-dien-3?-ol-d6
CAS:1246298-67-8
Purity:>99% Package:1MG;2.5MG
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| | Desmosterol-d6 Basic information |
| Product Name: | Desmosterol-d6 | | Synonyms: | Desmosterol-d6;CHOLESTA-5,24-DIEN-3-OL-D6;DESMOSTEROL-D6;cholesta-5,24-dien-3-ol-d6;24-dehydro Cholesterol-d6;[2H6]-Desmosterol;Desmosterol-26,26,26,27,27,27-d6;cholesta-5,24-dien-3β-ol-d6 | | CAS: | 1246298-67-8 | | MF: | C27H44O | | MW: | 384.63766 | | EINECS: | | | Product Categories: | Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals;Steroids | | Mol File: | 1246298-67-8.mol |  |
| | Desmosterol-d6 Chemical Properties |
| Melting point | 114-116°C | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) | | form | Solid | | color | Off-White to Light Beige |
| | Desmosterol-d6 Usage And Synthesis |
| Description | 24-dehydro Cholesterol-d6 is intended for use as an internal standard for the quantification of 24-dehydro cholesterol by GC- or LC-MS. 24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions. | | Uses | A labelled metabolite of Cholesterol (C432501). |
| | Desmosterol-d6 Preparation Products And Raw materials |
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