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4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid

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4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:TUG-424
CAS:1082058-99-8
Purity:99.77% Package:1mg;74USD|5mg;162USD|10mg;233USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:TUG 424;4-[2-(2-Methylphenyl)ethynyl]-benzenepropanoicacid
CAS:1082058-99-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: Shanghai HuanChuan Industry Co.,Ltd.  
Tel: 021-61478794
Email: sales@hcshhai.com
Products Intro: Product Name:4-[2-(2-Methylphenyl)ethynyl]-benzenepropanoicacid
CAS:1082058-99-8
Purity:95% Package:25g 100g
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Products Intro: Product Name:TUG 424
CAS:1082058-99-8
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
Company Name: MQ (shanghai) Pharmaceuticals Co., Ltd.  
Tel: 13761635123
Email: 1014988033@qq.com
Products Intro: Product Name:3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424
CAS:1082058-99-8
Purity:＞95% Package:1G，5G

4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid manufacturers

  • TUG-424
  • TUG-424 pictures
  • $74.00 / 1mg
  • 2024-11-12
  • CAS:1082058-99-8
  • Min. Order:
  • Purity: 99.77%
  • Supply Ability: 10g
4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Basic information
Product Name:4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid
Synonyms:4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid;TUG 424;CAY10587;3-(4-(o-Tolylethynyl)phenyl)propanoic acid;FODHWOBAQBTTFS-UHFFFAOYSA-N;Benzenepropanoic acid, 4-[2-(2-methylphenyl)ethynyl]-;TUG-424 >=98% (HPLC);3-(4-(o-Tolylethynyl)phenyl)propanoic acid , TUG-424
CAS:1082058-99-8
MF:C18H16O2
MW:264.32
EINECS:
Product Categories:
Mol File:1082058-99-8.mol
4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Structure
4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Chemical Properties
Boiling point 448.1±38.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMSO: >10mg/mL
pka4.62±0.10(Predicted)
form A crystalline solid
color White to off-white
Safety Information
Hazard Codes Xi,N
Risk Statements 36-50/53
Safety Statements 26-60-61
RIDADR UN 3077 9 / PGIII
WGK Germany 3
MSDS Information
4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Usage And Synthesis
Biological ActivityTUG-424 is expected to be useful in the exploration of FFA1 and may also be valuable as a lead structure for new potential antidiabetic therapeutics. TUG-424 significantly increased glucose-stimulated insulin secretion at 100 nM and may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. It enhanced glucose-stimulated insulin secretion in a r at beta-cell line already at 100 nM and from isolated mouse islets through FFA1.

GPR40 (now FFA1) was formerly an orphan GPCR whose endogenous ligands have recently been identified as free fatty acids (FFAs). The receptor appears to be involved in the pathophysiology of type 2 diabetes and is a drug target because of its role in FFA-mediated enhancement of glucose-stimulated insulin release.
4-[2-(2-methylphenyl)ethynyl]-benzenepropanoicacid Preparation Products And Raw materials
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