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(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone

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(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Ranirestat
CAS:147254-64-6
Purity:99% Package:5KG;1KG Remarks:C17H11BrFN3O4
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:ranirestat
CAS:147254-64-6
Purity:0.99 Package:1kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Ranirestat
CAS:147254-64-6
Purity:96.10% Package:2mg;399USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: RR Scientific LLC
Tel: +86-13917743231
Email: sales@rrscientific.com
Products Intro: Product Name:(R)-2'-(4-bromo-2-fluorobenzyl)-1'H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone
CAS:147254-64-6
Purity:0.98+ Package:100 g; 500 g; 1 kg; 5 kg; 10 kg;10kg+
Company Name: Shanghai Acmec Biochemical Technology Co., Ltd.
Tel: +86-18621343501; +undefined18621343501
Email: product@acmec-e.com
Products Intro: Product Name:Ranirestat
CAS:147254-64-6
Purity:98% Package:100mg, 50mg, 10mg, 5mg

(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone manufacturers

  • Ranirestat
  • Ranirestat pictures
  • $399.00 / 2mg
  • 2024-11-13
  • CAS:147254-64-6
  • Min. Order:
  • Purity: 96.10%
  • Supply Ability: 10g
(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Basic information
Product Name:(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone
Synonyms:(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone;Ranirestat;AS 3201;AS-3201;Spiro[pyrrolidine-3,4'(1'H)-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone,2'-[(4-broMo-2-fluorophenyl)Methyl]-, (3R)-;Ranirestat,AS-3201;Raniestat;AS-3201; SX-3201
CAS:147254-64-6
MF:C17H11BrFN3O4
MW:420.19
EINECS:
Product Categories:
Mol File:147254-64-6.mol
(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Structure
(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Chemical Properties
Melting point 192-193℃
Boiling point 702.7±60.0 °C(Predicted)
density 1.83
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: 20mg/mL, clear
form Solid
pka10.48±0.20(Predicted)
color Off-white to pink
optical activity[α]/D -5 to -10°, c =1.0 in methanol
Safety Information
MSDS Information
(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Usage And Synthesis
UsesRanirestat is an aldose reductase inhibitor used for the treatment of diabetic sensorimotor polyneuropathy.
Biological ActivityRanirest at (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via D-sorbitol. Ranirest at has been implicated in diabetic complications (cataract formation, retinopathy, neuropathy, nephropathy). Ranirest at prevents sorbitol accumulation and is thus hoped to be effective in the remedy of diabetic neuropathy.
(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone Preparation Products And Raw materials
Raw materials1211939-75-1-->159213-26-0-->4-BROMO-2-FLUOROBENZYLAMINE
Tag:(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone(147254-64-6) Related Product Information