Log in | Join Free | china | japan | germany

2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-

Request For Quotation
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:AF353
CAS:865305-30-2
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:AF 353
CAS:865305-30-2
Purity:>98% Package:25mg Remarks:BOC Sciences also provides custom synthesis services for AF 353.
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051
Email: joe@yuhengpharm.com
Products Intro: Product Name:5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)pyrimidine-2,4-diamine
CAS:865305-30-2
Package:1KG;25KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:AF-353；Ro-4;AF 353
CAS:865305-30-2
Purity:97.95% Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: CR Corporation Lomited
Tel:
Email: fred.wen@crcorporation.cn
Products Intro: Product Name:AF353
CAS:865305-30-2

2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- manufacturers

  • af-353
  • af-353 pictures
  • $100.00 / 1KG
  • 2022-02-25
  • CAS:865305-30-2
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100KG
  • af-353
  • af-353 pictures
  • $100.00 / 1Kg/Bag
  • 2022-02-25
  • CAS:865305-30-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10kg
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Basic information
Product Name:2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
Synonyms:2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-;AF 353;Ro 4;5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyriMidinediaMine;AF-353 (Ro-4);5-[5-Iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine;5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine hydrochloride Ro 4 hydrochloride;CS-2469
CAS:865305-30-2
MF:C14H17IN4O2
MW:400.21
EINECS:
Product Categories:Inhibitors
Mol File:865305-30-2.mol
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Structure
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Chemical Properties
Boiling point 510.2±60.0 °C(Predicted)
density 1.619±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 32 mg/mL (79.96 mM)
form Solid
pka6.89±0.10(Predicted)
color Light brown to brown
Safety Information
MSDS Information
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Usage And Synthesis
DescriptionAF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively). It is selective for P2X3 and P2X2/3 over P2X1, P2X2, P2X4, P2X5, and P2X7 (IC50 = >10 μM for all). It inhibits calcium flux in CHO-K1 cells expressing the rat P2X3 receptor and in 1321N1 cells expressing the human P2X3 and P2X2/3 receptors (IC50s = 8.91, 8.71, and 38.9 nM, respectively). AF-353 decreases the electrical signals in the detrusor, but not striated, muscle of the bladder in female rats.
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Preparation Products And Raw materials
Tag:2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-(865305-30-2) Related Product Information