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| | PF-3274167 Basic information |
| Product Name: | PF-3274167 | | Synonyms: | PF-3274167;PF-03274167;5-[3-[3-(2-Chloro-4-fluorophenoxy)-1-azetidinyl]-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl]-2-methoxypyridine;5-[3-[3-(2-chloro-4-fluorophenoxy)azetidin-1-yl]-5-(methoxymethyl)-1,2,4-triazol-4-yl]-2-methoxypyridine;Cligosiban;PF 3274167;PF3274167;PF-3274167(cligosiban);5-(3-(3-(2-Chloro-4-fluorophenoxy)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | | CAS: | 900510-03-4 | | MF: | C19H19ClFN5O3 | | MW: | 419.84 | | EINECS: | | | Product Categories: | | | Mol File: | 900510-03-4.mol |  |
| | PF-3274167 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: 18 mg/mL | | form | A crystalline solid | | color | Off-white to pink |
| | PF-3274167 Usage And Synthesis |
| Description | PF-3274167 is an oxytocin receptor antagonist (Ki = 9.5 nM). It is selective for the oxytocin receptor over the vasopressin receptors V1A and V2 (Kis = 1,120 and 10,000 nM, respectively). | | Uses | PF-3274167 functions as s triazole oxytocin antagonists. It also functions as a PET radiotracer of oxytocin receptors. |
| | PF-3274167 Preparation Products And Raw materials |
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