Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Ciproxifan hydrochloride CAS:1049741-81-2 Purity:>=98% (HPLC), solid Package:25MG Remarks:C6492-25MG
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Company Name: |
Shanghai Yanze Chemical Co., Ltd.
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Tel: |
021-13773155751 19975051755 |
Email: |
260924549@qq.com |
Products Intro: |
Product Name:Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride CAS:1049741-81-2 Purity:99% Package:10T
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing1@energy-chemical.com |
Products Intro: |
Product Name:Ciproxifanhydrochloride CAS:1049741-81-2 Purity:NULL Package:10mg;5mg;25mg;5mg Remarks:NULL
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| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Basic information |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Chemical Properties |
storage temp. | 2-8°C | solubility | DMSO: soluble30mg/mL | form | solid | color | off-white |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Usage And Synthesis |
Uses | Ciproxifan Hydrochloride is a novel chemical series of human histamine H3-receptor antagonists. | Biochem/physiol Actions | Ciproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. Ciproxifan appears to be an orally bioavailable, extremely potent and selective H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders. |
| Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone hydrochloride Preparation Products And Raw materials |
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