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| (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Basic information |
| (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Chemical Properties |
Melting point | 238 - 240°C | Boiling point | 551.0±50.0 °C(Predicted) | density | 1.249±0.06 g/cm3(Predicted) | storage temp. | Refrigerator | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | pka | 6.06±0.60(Predicted) | form | Solid | color | White to Off-White |
| (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Usage And Synthesis |
Uses | Tofacitinib Citrate Impurity is derived from (3R,?4R)?-N,?4-?Dimethyl-?1-?benzyl?-3-?piperidinamine (D464895), which is a reagent used in the preparation of Janus tyrosine kinase inhibitors for the treatment of autoimmune diseases. |
| (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Preparation Products And Raw materials |
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