(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile

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Products Intro: Product Name:Tofacitinib Impurity 18
CAS:1640971-60-3
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Products Intro: Product Name:(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile
CAS:1640971-60-3
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CAS:1640971-60-3
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Products Intro: Product Name:(3R,4R)-3-[(6-AMINO-4-PYRIMIDINYL)METHYLAMINO]-4-METHYL-Β-OXO-1-PIPERIDINEPROPANENITRILE
CAS:1640971-60-3
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Products Intro: Product Name:tofacitinib iMpurity
CAS:1640971-60-3

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile manufacturers

(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Basic information
Product Name:(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile
Synonyms:ofacitinib iMpurity;Tofacitinib Citrate Impurity;Tofacitinib Impurity 11;Tofacitinib Impurity 14;Tofacitinib Impurity 15;Tofacitinib Impurity 18;Tofacitinib Impurity 9;3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl) (methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate-one
CAS:1640971-60-3
MF:C14H20N6O
MW:288.35
EINECS:
Product Categories:ZJ;ZY
Mol File:1640971-60-3.mol
(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Structure
(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Chemical Properties
Melting point 238 - 240°C
Boiling point 551.0±50.0 °C(Predicted)
density 1.249±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka6.06±0.60(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Usage And Synthesis
UsesTofacitinib Citrate Impurity is derived from (3R,?4R)?-N,?4-?Dimethyl-?1-?benzyl?-3-?piperidinamine (D464895), which is a reagent used in the preparation of Janus tyrosine kinase inhibitors for the treatment of autoimmune diseases.
(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile Preparation Products And Raw materials
Tag:(3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile(1640971-60-3) Related Product Information
Etoricoxib IMpurity 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone BENZOOXAZOL-2-YLAMINE (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester 7-(4-Hydroxybutoxy-4,4-d2)-2(1H)-quinolinone Sorafenib IMpurity Rocuronium Bromide Impurity Piperacillin Impurity Sildenafil Aldehyde IMpurity Sulbactam Impurity Tenofovirdisoproxil Impurity LUMACAFTOR IMPURITY Dapagliflozin iMpurity N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine (3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile Tofacitinib related coMpound 2