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| 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Basic information |
Product Name: | 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine | Synonyms: | 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine;5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine;Desmethyl-VS-5584;5-[2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine;DESMETHYL VS 5584; DESMETHYL VS5584;2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-;VS-5584 analog;Desmethyl-SB2343,Dual inhibitor,Selectivity,DesmethylVS5584,Mammalian target of Rapamycin,PI3K,Phosphoinositide 3-kinase,mTOR,Inhibitor,Desmethyl VS 5584,inhibit | CAS: | 1246535-95-4 | MF: | C16H20N8O | MW: | 340.38 | EINECS: | | Product Categories: | | Mol File: | 1246535-95-4.mol | ![5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Structure](CAS/20180808/GIF/1246535-95-4.gif) |
| 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Chemical Properties |
Boiling point | 669.3±65.0 °C(Predicted) | density | 1.52±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Chloroform: 0.5mg/mL | form | A solid | pka | 3.94±0.10(Predicted) |
| 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Usage And Synthesis |
Description | VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively). It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 . | Uses | An intermediate in the preparation of purine compounds as therapeutic kinase inhibitors. |
| 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Preparation Products And Raw materials |
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