|
|
| | Apixaban Impurity BMS-724914 Basic information |
| Product Name: | Apixaban Impurity BMS-724914 | | Synonyms: | 6-(4-((5-aMino-5-oxopentyl)aMino)phenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide;BMS-719288-01;Apixaban impurity 3/6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)- 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3- carboxamide;6-[4-[(5-amino-5-oxopentyl)amino]phenyl]-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide;Apixaban-6;5-({4-[3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-6-yl]phenyl}amino)pentanamide;1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 6-[4-[(5-amino-5-oxopentyl)amino]phenyl]-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-;Apixaban Impurity F | | CAS: | 2187409-01-2 | | MF: | C25H28N6O4 | | MW: | 476.53 | | EINECS: | | | Product Categories: | | | Mol File: | 2187409-01-2.mol |  |
| | Apixaban Impurity BMS-724914 Chemical Properties |
| Boiling point | 802.1±65.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | pka | 15.05±0.20(Predicted) |
| | Apixaban Impurity BMS-724914 Usage And Synthesis |
| Uses | Des(2-oxo-1-piperidinyl) 6-(4-(5-Amino-5-oxopentyl)) Apixaban is a metabolite of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. |
| | Apixaban Impurity BMS-724914 Preparation Products And Raw materials |
|