- MSX-122
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- $58.00 / 5mg
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2024-11-19
- CAS:897657-95-3
- Min. Order:
- Purity: 98.78%
- Supply Ability: 10g
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| | MSX-122 Basic information |
| Product Name: | MSX-122 | | Synonyms: | MSX-122;MSX 222;MSX-122;MSX122;CS-2430;MSX-122;MSX 122;MSX122;N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]pyrimidin-2-amine;1,4-Benzenedimethanamine, N1,N4-di-2-pyrimidinyl-;inhibit,MSX-122,CXC chemokine receptors,Inhibitor,CXCR | | CAS: | 897657-95-3 | | MF: | C16H16N6 | | MW: | 292.35 | | EINECS: | | | Product Categories: | | | Mol File: | 897657-95-3.mol |  |
| | MSX-122 Chemical Properties |
| Melting point | 219 °C | | Boiling point | 566.9±60.0 °C(Predicted) | | density | 1.313±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO:0.2(Max Conc. mg/mL);0.7(Max Conc. mM) | | form | A crystalline solid | | pka | 3.82±0.10(Predicted) | | color | Light yellow to yellow |
| | MSX-122 Usage And Synthesis |
| Uses | CXCR4 is involved with the recruitment of inflammatory cells to inflammation sites. MSX-122 is a CXCR4 inhibitor. It exhibits potential antineoplastic and antiviral activities. | | in vivo | MSX-122 (10 mg/kg, i.p.) blocks inflammation induced by carrageenan and lung fibrosis induced by bleomycin in mice. MSX-122 (4 mg/kg, i.p., daily) blocks metastasis in an experimental animal model of breast cancer metastasis. Furthermore, MSX-122 (10 mg/kg i.p., daily) significantly decreases the numbers of hepatic micrometastases[1]. | | IC 50 | CXCR4/CXCL12: ~10 nM (IC50) |
| | MSX-122 Preparation Products And Raw materials |
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